Ranjan Lab Research
The Ranjan Laboratory is located in the Nora Eccles Harrison Cardiovascular Research and Training Institute (CVRTI) at the University of Utah, where it studies tissue- and organ-scale physiology and pathophysiology in cardiac arrhythmias.
In Dr. Ranjan’s own words, the lab’s research focuses on “tissue- and organ-scale physiology and pathophysiology in conditions such as atrial fibrillation, atypical left atrial flutter, ventricular tachycardia, and cardiac stereotactic radiotherapy,” integrating “cardiac computational modeling, machine learning, preclinical experimental models, cardiac magnetic resonance imaging, biochemical assays, electrophysiological mapping techniques, and human clinical data to study disease progression, develop treatment strategies, and advance understanding of cardiac physiology.”
The group uses personalized computational models to deliver optimal ablation lesions and works on identifying mechanisms underlying arrhythmias using genetically modified models.
Research Areas
The Ranjan Laboratory integrates cardiac computational modeling, machine learning, preclinical experimental models, cardiac magnetic resonance imaging, biochemical assays, electrophysiological mapping techniques, and human clinical data to study disease progression, develop treatment strategies, and advance understanding of cardiac physiology.
His clinical interests include ablation of complex cardiac arrhythmias — atrial fibrillation, ventricular tachycardia, and supraventricular tachycardia — and cardiac device-based therapies such as cardiac resynchronization therapy (CRT), implantable cardioverter-defibrillators (ICDs), and pacemakers.
Atrial FibrillationStudying tissue- and organ-scale physiology and pathophysiology in atrial fibrillation: how AF initiates, progresses, and recurs after ablation.
Personalized Computational Modeling to Guide AblationPatient-specific computational models to deliver optimal ablation lesions for atrial arrhythmias.
Atypical Left Atrial Flutter and Ventricular TachycardiaIdentifying mechanisms underlying these arrhythmias and developing treatment strategies, using genetically modified and preclinical models.
Cardiac Stereotactic Radiotherapy and Integrative ApproachesCombining computational modeling, machine learning, cardiac magnetic resonance imaging, biochemical assays, electrophysiological mapping, and human clinical data to study disease progression and advance cardiac physiology.
Leadership
Ravi Ranjan, MD, PhD is a tenured Professor of Medicine and Section Chief of Cardiac Electrophysiology at the University of Utah, and an Investigator at the Nora Eccles Harrison Cardiovascular Research and Training Institute (CVRTI). He is board certified in Cardiovascular Disease and Clinical Cardiac Electrophysiology.
Mentorship
Dr. Ranjan is listed as a faculty mentor with the University of Utah Office of Undergraduate Research.
